My clinical focuses are echocardiography, particularly fetal echocardiography, management of congenital heart disease, and Kawasaki Disease.

MEDIA

Caregiver Profile

Caregiver Profile

Meet Kevin G. Friedman

EDUCATION

Undergraduate Degree

  • University of Notre Dame , 2000 , South Bend , IN

Medical School

  • Harvard Medical School , 2004 , Boston , MA

Internship

  • The Children's Hospital at University of Colorado , 2005 , Denver , CO

Residency

  • The Children's Hospital at University of Colorado , 2007 , Denver , CO

Fellowship

Pediatric Cardiology
  • Boston Children's Hospital , 2010 , Boston , MA

Fellowship

Chief Fellow, Pediatric Cardiology
  • Boston Children's Hospital , 2011 , Boston , MA

Fellowship

Senior Fellow, Non-Invasive Imaging
  • Boston Children's Hospital , 2012 , Boston , MA

PROFESSIONAL HISTORY

I am a pediatric and fetal cardiologist at Boston Children’s Hospital with focus in non-invasive imaging at Boston Children’s Hospital. My clinical focuses are echocardiography, particularly fetal echocardiography, management of congenital heart disease, and Kawasaki Disease.


My research interests include diastolic function in left-sided congenital heart disease, fetal diagnosis and management of complex congenital heart disease, and Kawasaki Disease.

CERTIFICATIONS

  • American Board of Pediatrics, General Pediatrics
  • American Board of Pediatrics, Pediatric Cardiology

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19. JAMA. 2021 Feb 24. View abstract
  2. Socioeconomic and Racial/Ethnic Disparities in Multisystem Inflammatory Syndrome. Pediatrics. 2021 Feb 18. View abstract
  3. Reply to Prophylactic Anticoagulation: Comment on the ACR Guidance for Management of Multisystem Inflammatory Syndrome in Children. Arthritis Rheumatol. 2021 Feb 14. View abstract
  4. Prenatal Diagnosis of Congenital Heart Disease the Past, Present, and Future. Current Treatment Options in Cardiovascular Medicine. 2021; 2(23):1-10. View abstract
  5. Importance of Noninvasive Cardiac Output Measurement in Children: Feasibility or Applicability? J Cardiothorac Vasc Anesth. 2021 Jan 21. View abstract
  6. Late gestation predictors of a postnatal biventricular circulation after fetal aortic valvuloplasty. Prenat Diagn. 2021 Jan 18. View abstract
  7. Parent and Physician Understanding of Prognosis in Hospitalized Children With Advanced Heart Disease. J Am Heart Assoc. 2021 Jan 19; 10(2):e018488. View abstract
  8. Comparison Between Currently Recommended Long-Term Medical Management of Coronary Artery Aneurysms After Kawasaki Disease and Actual Reported Management in the Last Two Decades. Pediatr Cardiol. 2021 Jan 13. View abstract
  9. Multiple Emergency Department visits for a diagnosis of Kawasaki Disease: An Examination of Risk Factors and Outcomes. J Pediatr. 2021 Jan 13. View abstract
  10. American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 2. Arthritis Rheumatol. 2020 Dec 05. View abstract
  11. Review of Cardiac Involvement in Multisystem Inflammatory Syndrome in Children. Circulation. 2021 01 05; 143(1):78-88. View abstract
  12. Difference in the prevalence of intracardiac thrombus on the first presentation of atrial fibrillation versus flutter in the pediatric and congenital heart disease population. J Cardiovasc Electrophysiol. 2020 Dec; 31(12):3243-3250. View abstract
  13. Regional Brain Growth Trajectories in Fetuses with Congenital Heart Disease. Ann Neurol. 2021 01; 89(1):143-157. View abstract
  14. Distinct clinical and immunological features of SARS-CoV-2-induced multisystem inflammatory syndrome in children. J Clin Invest. 2020 11 02; 130(11):5942-5950. View abstract
  15. Cardiac Dysfunction in Multisystem Inflammatory Syndrome in Children: A Call to Action. J Am Coll Cardiol. 2020 10 27; 76(17):1962-1964. View abstract
  16. American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 1. Arthritis Rheumatol. 2020 11; 72(11):1791-1805. View abstract
  17. Primary adjunctive corticosteroid therapy is associated with improved outcomes for patients with Kawasaki disease with coronary artery aneurysms at diagnosis. Arch Dis Child. 2021 Mar; 106(3):247-252. View abstract
  18. Ascending Aortoplasty in Pediatric Patients Undergoing Aortic Valve Procedures. Ann Thorac Surg. 2020 Sep 16. View abstract
  19. Atrioventricular Block in Children With Multisystem Inflammatory Syndrome. Pediatrics. 2020 11; 146(5). View abstract
  20. Cardiac manifestations in SARS-CoV-2-associated multisystem inflammatory syndrome in children: a comprehensive review and proposed clinical approach. Eur J Pediatr. 2021 Feb; 180(2):307-322. View abstract
  21. Update on the Management of Kawasaki Disease. Pediatr Clin North Am. 2020 10; 67(5):811-819. View abstract
  22. Medium-Term Complications Associated With Coronary Artery Aneurysms After Kawasaki Disease: A Study From the International Kawasaki Disease Registry. J Am Heart Assoc. 2020 08 04; 9(15):e016440. View abstract
  23. Case Report: Hybrid Approach to Neonatal Repair of Large Symptomatic Congenital Coronary Artery Fistula. JTCVS Techniques. 2020. View abstract
  24. Association of Isolated Congenital Heart Disease with Fetal Brain Maturation. AJNR Am J Neuroradiol. 2020 08; 41(8):1525-1531. View abstract
  25. Low-Molecular-Weight Heparin vs Warfarin for Thromboprophylaxis in Children With Coronary Artery Aneurysms After Kawasaki Disease: A Pragmatic Registry Trial. Can J Cardiol. 2020 Oct; 36(10):1598-1607. View abstract
  26. Early Infant Symptomatic Patients With Tetralogy of Fallot With Absent Pulmonary Valve: Pulmonary Artery Management and Airway Stabilization. Ann Thorac Surg. 2020 11; 110(5):1644-1650. View abstract
  27. Children at Risk: Multisystem Inflammatory Syndrome and COVID-19. JACC Case Rep. 2020 Jul 15; 2(9):1271-1274. View abstract
  28. Pulmonary Valve Reconstruction Using the Ozaki Leaflet Reconstructive Techniques. Ann Thorac Surg. 2021 01; 111(1):e19-e21. View abstract
  29. 1.5-Ventricle Repair Using Left Ventricle as the Subpulmonary Ventricle. Ann Thorac Surg. 2020 12; 110(6):e529-e530. View abstract
  30. Apixaban for treatment of intracardiac thrombosis in children with congenital heart disease. Interact Cardiovasc Thorac Surg. 2020 06 01; 30(6):950-951. View abstract
  31. Aortic uncrossing and tracheobronchopexy corrects tracheal compression and tracheobronchomalacia associated with circumflex aortic arch. J Thorac Cardiovasc Surg. 2020 Sep; 160(3):796-804. View abstract
  32. Management of Myocardial Infarction in Children with Giant Coronary Artery Aneurysms after Kawasaki Disease. J Pediatr. 2020 06; 221:230-234. View abstract
  33. Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome: A Decision Analysis. Circ Cardiovasc Qual Outcomes. 2020 04; 13(4):e006127. View abstract
  34. Low mortality in fetal supraventricular tachycardia: Outcomes in a 30-year single-institution experience. J Cardiovasc Electrophysiol. 2020 May; 31(5):1105-1113. View abstract
  35. Fetal cardiac interventions: Where do we stand? Arch Cardiovasc Dis. 2020 Feb; 113(2):121-128. View abstract
  36. Fetal cardiac intervention-Perspectives from a single center. Prenat Diagn. 2020 03; 40(4):415-423. View abstract
  37. Echocardiographic Diagnosis of Anomalous Single Coronary Artery from the Pulmonary Artery: Use of Bubble Contrast Echocardiography. Pediatr Cardiol. 2020 Jan; 41(1):215-216. View abstract
  38. Early-Emerging Sulcal Patterns Are Atypical in Fetuses with Congenital Heart Disease. Cereb Cortex. 2019 07 22; 29(8):3605-3616. View abstract
  39. Impact of Socioeconomic Status on Outcomes of Patients with Kawasaki Disease. J Pediatr. 2019 09; 212:87-92. View abstract
  40. Current Treatment Options in Pediatrics. Acute Kawasaki Disease Therapy. 2019; [Epub ahead of print]. View abstract
  41. Risk Model Development and Validation for Prediction of Coronary Artery Aneurysms in Kawasaki Disease in a North American Population. J Am Heart Assoc. 2019 06 04; 8(11):e011319. View abstract
  42. Treatment Intensification in Patients With Kawasaki Disease and Coronary Aneurysm at Diagnosis. Pediatrics. 2019 06; 143(6). View abstract
  43. Type B Interrupted Right Aortic Arch: Diagnostic and Surgical Approaches. Ann Thorac Surg. 2019 01; 107(1):e41-e43. View abstract
  44. Ascending Aorta Size at Birth Predicts White Matter Microstructure in Adolescents Who Underwent Fontan Palliation. J Am Heart Assoc. 2018 12 18; 7(24):e010395. View abstract
  45. Association of Initially Normal Coronary Arteries With Normal Findings on Follow-up Echocardiography in Patients With Kawasaki Disease. JAMA Pediatr. 2018 12 01; 172(12):e183310. View abstract
  46. Left Atrial Size and Function in Patients With Congenital Aortic Valve Stenosis. Am J Cardiol. 2018 11 01; 122(9):1541-1545. View abstract
  47. Echocardiographic predictors of neonatal illness severity in fetuses with critical left heart obstruction with intact or restrictive atrial septum. Prenat Diagn. 2018 09; 38(10):788-794. View abstract
  48. Improved technical success, postnatal outcome and refined predictors of outcome for fetal aortic valvuloplasty. Ultrasound Obstet Gynecol. 2018 08; 52(2):212-220. View abstract
  49. Impact of a Composite Valved RV-PA Graft After Stage 1 Palliation. Ann Thorac Surg. 2018 11; 106(5):1452-1459. View abstract
  50. Clinical and Hemodynamic Results After Conversion from Single to Biventricular Circulation After Fetal Aortic Stenosis Intervention. Am J Cardiol. 2018 08 01; 122(3):511-516. View abstract
  51. Preoperative Physiology, Imaging, and Management of Interrupted Aortic Arch. Semin Cardiothorac Vasc Anesth. 2018 Sep; 22(3):265-269. View abstract
  52. Early hemodynamic changes after fetal aortic stenosis valvuloplasty predict biventricular circulation at birth. Prenat Diagn. 2018 03; 38(4):286-292. View abstract
  53. Myocardial injury in fetal aortic stenosis: Insights from amniotic fluid analysis. Prenat Diagn. 2018 02; 38(3):190-195. View abstract
  54. Indomethacin induced ductus arteriosus closure in midgestation fetus. Clin Case Rep. 2018 03; 6(3):506-508. View abstract
  55. Is There More to Zika? Complex Cardiac Disease in a Case of Congenital Zika Syndrome. Neonatology. 2018; 113(2):177-182. View abstract
  56. Coronary Stenosis after Kawasaki Disease: Size Matters. J Pediatr. 2018 03; 194:8-10. View abstract
  57. Fetal interventions for structural heart disease. Echocardiography. 2017 12; 34(12):1834-1841. View abstract
  58. Cardiac output and blood flow redistribution in fetuses with D-loop transposition of the great arteries and intact ventricular septum: insights into pathophysiology. Ultrasound Obstet Gynecol. 2017 Nov; 50(5):612-617. View abstract
  59. Resource reduction in pediatric chest pain: Standardized clinical assessment and management plan. Congenit Heart Dis. 2018 Jan; 13(1):46-51. View abstract
  60. Impact of standardized clinical assessment and management plans on resource utilization and costs in children after the arterial switch operation. Congenit Heart Dis. 2017 Dec; 12(6):768-776. View abstract
  61. Safety and Efficacy of Warfarin Therapy in Kawasaki Disease. J Pediatr. 2017 10; 189:61-65. View abstract
  62. Coronary Artery Aneurysms in Kawasaki Disease: Risk Factors for Progressive Disease and Adverse Cardiac Events in the US Population. J Am Heart Assoc. 2016 09 15; 5(9). View abstract
  63. Cardiac Findings in the Fetus with Cerebral Arteriovenous Malformation Are Associated with Adverse Outcome. Fetal Diagn Ther. 2017; 41(2):108-114. View abstract
  64. Systolic-diastolic functional coupling in healthy children and in those with dilated cardiomyopathy. J Appl Physiol (1985). 2016 Jun 01; 120(11):1301-18. View abstract
  65. Needles in Hay II: Detecting Cardiac Pathology by the Pediatric Chest Pain Standardized Clinical Assessment and Management Plan. Congenit Heart Dis. 2016 Sep; 11(5):396-402. View abstract
  66. Coronary Artery Aneurysm Measurement and Z Score Variability in Kawasaki Disease. J Am Soc Echocardiogr. 2016 Feb; 29(2):150-7. View abstract
  67. Differentiating standardized clinical assessment and management plans from clinical practice guidelines. Acad Med. 2015 Aug; 90(8):1002. View abstract
  68. Prevalence of Undiagnosed Structural Heart Disease in Children Undergoing Echocardiography for Kawasaki Disease. Clin Pediatr (Phila). 2016 Jun; 55(6):557-9. View abstract
  69. Left Ventricular Remodeling and Function in Children with Biventricular Circulation After Fetal Aortic Valvuloplasty. Pediatr Cardiol. 2015 Oct; 36(7):1502-9. View abstract
  70. Prenatal diagnosis of transposition of the great arteries over a 20-year period: improved but imperfect. Ultrasound Obstet Gynecol. 2015 Jun; 45(6):678-82. View abstract
  71. Gathering and learning from relevant clinical data: a new framework. Acad Med. 2015 Feb; 90(2):143-8. View abstract
  72. Fetal aortic valvuloplasty for evolving hypoplastic left heart syndrome: postnatal outcomes of the first 100 patients. Circulation. 2014 Aug 19; 130(8):638-45. View abstract
  73. Perinatal and infant outcomes of prenatal diagnosis of heterotaxy syndrome (asplenia and polysplenia). Am J Cardiol. 2014 Aug 15; 114(4):612-7. View abstract
  74. Left ventricular diastolic function and characteristics in fetal aortic stenosis. Am J Cardiol. 2014 Jul 01; 114(1):122-7. View abstract
  75. Perinatal outcome in fetuses with heterotaxy syndrome and atrioventricular block or bradycardia. Pediatr Cardiol. 2014 Aug; 35(6):906-13. View abstract
  76. Acute outcomes after introduction of a standardized clinical assessment and management plan (SCAMP) for balloon aortic valvuloplasty in congenital aortic stenosis. Congenit Heart Dis. 2014 Jul-Aug; 9(4):316-25. View abstract
  77. Midgestation fetal pulmonary annulus size is predictive of outcome in tetralogy of fallot. Congenit Heart Dis. 2014 May-Jun; 9(3):187-93. View abstract
  78. Chest pain and syncope in children: a practical approach to the diagnosis of cardiac disease. J Pediatr. 2013 Sep; 163(3):896-901.e1-3. View abstract
  79. Standardized Clinical Assessment And Management Plans (SCAMPs) provide a better alternative to clinical practice guidelines. Health Aff (Millwood). 2013 May; 32(5):911-20. View abstract
  80. Left ventricular diastolic function in children and young adults with congenital aortic valve disease. Am J Cardiol. 2013 Jan 15; 111(2):243-9. View abstract
  81. Left ventricular remodeling and improvement in diastolic function after balloon aortic valvuloplasty for congenital aortic stenosis. Circ Cardiovasc Interv. 2012 Aug 01; 5(4):549-54. View abstract
  82. Dynamic evolution of practice guidelines: analysis of deviations from assessment and management plans. Pediatrics. 2012 Jul; 130(1):93-8. View abstract
  83. Resource Utilization Reduction for Evaluation of Chest Pain in Pediatrics Using a Novel Standardized Clinical Assessment and Management Plan (SCAMP). J Am Heart Assoc. 2012 Apr; 1(2). View abstract
  84. Provider attitudes toward Standardized Clinical Assessment and Management Plans (SCAMPs). Congenit Heart Dis. 2011 Nov-Dec; 6(6):558-65. View abstract
  85. Management of pediatric chest pain using a standardized assessment and management plan. Pediatrics. 2011 Aug; 128(2):239-45. View abstract
  86. Postnatal left ventricular diastolic function after fetal aortic valvuloplasty. Am J Cardiol. 2011 Aug 15; 108(4):556-60. View abstract
  87. Risk factors for failed staged palliation after bidirectional Glenn in infants who have undergone stage one palliation. Eur J Cardiothorac Surg. 2011 Oct; 40(4):1000-6. View abstract
  88. Resource utilization after introduction of a standardized clinical assessment and management plan. Congenit Heart Dis. 2010 Jul-Aug; 5(4):374-81. View abstract
  89. A novel approach to gathering and acting on relevant clinical information: SCAMPs. Congenit Heart Dis. 2010 Jul-Aug; 5(4):343-53. View abstract
  90. Kawasaki disease in a pediatric intensive care unit: a case-control study. Pediatrics. 2008 Oct; 122(4):e786-90. View abstract
  91. An unusual cause of pediatric hypertension. J Pediatr. 2007 Aug; 151(2):206-12. View abstract