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Research at Boston Children's Hospital

The research enterprise at Boston Children’s Hospital, comprising more than 3,000 researchers, is the world’s largest at a pediatric center. Our work is fueled by a deep understanding of disease biology coupled with world-class discovery platforms, including genetics and genomics, gene editing, bioinformatics, proteomics, bioengineering, image analysis, biobanks, disease-specific stem cell lines, and a range of animal models. We have special expertise in rare disease discovery, a robust Translational Research Program and large, diverse patient populations for clinical research and trials.

Virtual Research Recruiting Week

A black girl standing in white shirt and pink skirt stands in front of windows in her ballerina pose.

Monday, February 6, 2023 to February , February 9, 2023

Boston Children's Hospital, the #1 ranked pediatric hospital in the nation, invites top-preforming graduating seniors to learn firsthand about some of the breakthrough research currently being conducted. Attendees will have the opportunity to network in a virtual setting directly with hiring managers and Principal Investigators and hear from a panel of renowned researchers. 

More than 3,000 researchers and scientific staff

1 million square feet of research space — and growing

3,400 articles/year in peer reviewed journals — the most of any pediatric hospital

Lasker Foundation Announces 2022 Lasker Award Winners

Congratulations to Timothy A. Springer for winning the 2022 Lasker Award for discoveries concerning integrins – key mediators of cell-matrix and cell-cell interactions in physiology and diseases.

Learn more about the Lasker Award

Advancing microglial science

Immune-like microglia protect the brain and help sculpt the brain’s wiring. On the flip side, they can drive brain inflammation, synapse loss, and pathology in diseases like Alzheimer's. Neuroscientist Beth Stevens, PhD, and international colleagues create a comprehensive “roadmap” for studying these complicated cells.

LEARN MORE about advancing microglial science

New insight into dietary approaches for epilepsy

Since ancient times, fasting has been believed to curb seizures, but the reasons have been mysterious. Research led by Christopher Yuskaitis, MD, PhD in the Epilepsy Program gives insight on how fasting affects the brain. It could lead the way to new epilepsy treatment that don’t involve fasting.

LEARN MORE about dietary approaches for epilepsy

Preventing ‘chemo brain’ with antioxidants targeting the spinal fluid

Many children receiving cancer chemotherapy suffer from “chemo brain,” impairing memory, attention, and learning. New work led by Maria Lehtinen, PhD, and Naama Kanarek, PhD suggests the possibility of using antioxidants, potentially given along with the chemotherapy, to spare the brain from chemo’s toxic effects.

LEARN MORE about preventing chemo brain

An image worth 1,000 words?

The 2021 Science Media Exhibition solicited more than 40 science image submissions from research laboratories and programs throughout Boston Children’s Hospital. The images here were presented live during a virtual event held in June in conjunction with Dr. M. Judah Folkman Research Day.